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IL-12 is a disulfide-linked heterodimer composed of two subunits: a 40 kDa (p40) and a 35 kDa (p35) glycoprotein
and its high expression is essential for Treg cells to maintain their immunosuppressive function
Disorders associated with it include acute thoracic syndrome and sickle cell disease
because of the presence of J chain
Ac-LEVD-pNA and pNA need to be stored in the dark
Pacific Blue Rat Anti-Mouse CD16/CD32 Antibody (S-R368) IHC Kits IL-12 is a disulfide-linked heterodimerProduct Specification Host Rat Antigen CD16 CD32 Synonyms Low affinity immunoglobulin gamma Fc region receptor III; IgG Fc receptor III; Fc gamma RIII (FcRIII); Fcgr3; Low affinity immunoglobulin gamma Fc region receptor II; Fc gamma receptor IIB; Fc gamma RII; Fc gamma RIIB; FcRII; IgG Fc receptor II beta; Lymphocyte antigen 17 (Ly 17); Fcgr2; Fcgr2b; Ly 17 Location Cell membrane Accession P08508P08101 Clone Number S R368 Antibody Type Rat mAb